Benjamin Kidder’s lab focuses on epigenetic mechanisms of stem cell self-renewal and differentiation, transcriptional networks, genome stability and cancer epigenetics, and reprogramming and transdifferentiation. We integrate  experimental data with computational analysis of epigenomic and transcriptomic data.

We are members of the Department of Oncology at Wayne State University and the Barbara Ann Karmanos Cancer Institute.

News:

4/2019: Contribution of H3K4 demethylase KDM5B to nucleosome organization in embryonic stem cells revealed by micrococcal nuclease sequencing paper was published

Capture

8/2018: Identification of H4K20me3 and H3K4me3-associated RNAs using CARIP-Seq paper was published

CARIP-Seq_circos

7/2018: Derivation of maEpiSCs from haploid blastocysts paper was recently published!

EpiSC_haploid_blastocyst

7/2018: Novel H4K20me3/H3K4me3 bivalent domain paper was published!

H4K20me3_bivalent

H4K20me3_bivalent_heatmap

5/2018: KDM5B TSC paper was recently published!

KDM5B_TSC

3/2018: iPSC cancer immunotherapy was published in collaboration with Dr. Restifo’s lab at the NCI.

ipsc.png

1/2018: Jacob Lindquist joined the lab as a Ph.D. candidate in the Cancer Biology Graduate program. Welcome!

11/2017: OCT4 paper, which describes ESC self-renewal in the absence of LIF, has been published.

OCT4-1.PNGOCT4-2OCT4

9/2017: SMYD5 cancer/genome stability paper was recently accepted for publication, and can be found online!

circos-smyd5circos-smyd5-SKYcircos-smyd5-HCA

8/2017: Besa Xhabija has obtained a faculty position in the Department of Chemistry and Biochemistry, University of Michigan- Flint

4/2017: KDM5B paper was recently published! PMID: 28402433

kdm5b-elongation

3/2017: Congrats to John Campeanu who received a “Medical Student Summer Research Fellowship”

2/2017: Smyd5 paper was recently published PMID: 28250819.

smyd5

Copyright © 2015-2019 Benjamin Kidder

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