Benjamin Kidder’s lab focuses on epigenetic mechanisms of stem cell self-renewal and differentiation, transcriptional networks, genome stability and cancer epigenetics, and reprogramming and transdifferentiation. We integrate experimental data with computational analysis of epigenomic and transcriptomic data.
4/2022: Our paper, H3K4 demethylase KDM5B regulates cancer cell identity and epigenetic plasticity, was published in Oncogene!
3/2021: Our Nature Communications paper, Integrative pan cancer analysis reveals epigenomic variation in cancer type and cell specific chromatin domains, was published.
12/2020: H4K20me3 methyltransferase SUV420H2 shapes the chromatin landscape of pluripotent embryonic stem cells paper was published in Development.
8/2019: KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer paper was published
8/2018: Identification of H4K20me3 and H3K4me3-associated RNAs using CARIP-Seq paper was published
7/2018: Derivation of maEpiSCs from haploid blastocysts paper was recently published!
7/2018: Novel H4K20me3/H3K4me3 bivalent domain paper was published!
5/2018: KDM5B TSC paper was recently published!
3/2018: iPSC cancer immunotherapy was published in collaboration with Dr. Restifo’s lab at the NCI.
11/2017: OCT4 paper, which describes ESC self-renewal in the absence of LIF, has been published.
8/2017: Besa Xhabija has obtained a faculty position in the Department of Chemistry and Biochemistry, University of Michigan- Flint
3/2017: Congrats to John Campeanu who received a “Medical Student Summer Research Fellowship”
Copyright © 2015-2020 Benjamin Kidder